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Have you used PARP Inhibitors to treat your ovarian cancer?

PARP inhibitors have been used as maintenance therapy to treat ovarian cancer since 2014. Have you used PARP Inhibitors as a form of treatment?

  1. Ive been on Lynparza 400mg daily and Ned for a couple years after Stage IV Ovarian Cancer dx Jan 2023. Joint pain, fatigue but nothing that I cant tolerate. I was first placed on Zejula but I was left with debilitating blood and platelet counts causing me to be hospitalized with transfusions of both.

    1. Hi . Welcome to the community! I'm glad the Lynparza side effects are tolerable. How long does your doctor want you to remain on it? Warm wishes. - Lori (Team Member)

  2. No.

    1. , are you happy with your current treatment protocol? How are you doing today? - Warmly, Donna (Team Member)

  3. Yes, ZEJULA. Started on 300mg daily and developed critical level thrombocytopenia and required a week of hospitalization and platelet transfusion. Held for a month and restarted on 200mg daily and developed severe anemia with hemoglobin 6.7 requiring blood transfusion. Dose held for a month and now restarted at 100mg daily. Additionally, the fatigue has been THOROUGHLY DEBILITATING! But I am thankful to be alive.

    1. thank you so much for sharing. This sounds like such a rollercoaster. How have you been doing lately? And ugh fatigue is the WORST. Warmly, Rackel (Team Member)

    2. , that sounds like it was a terribly rough experience! And fatigue is so difficult to live with. How are you doing today? - Warmly, Donna (Team Member)

  4. Yes, first time around zejula, too many side effects. 2nd go round just started Rubraca

    1. what side effects were you experiencing and how has it been so far on rubraca? Warmly, Rackel (Team Member)

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